Neuronal circuits that regulate feeding behavior and metabolism

Neuronal Circuits and Reinforcement Mechanisms Underlying Feeding Behaviour

Neuronal elements that mediate escape swimming and suppress feeding behavior in the predatory sea slug Pleurobranchaea.

1. The white, bilaterally paired A1 interneurons of the cerebropleural ganglion of Pleurobranchaea californica fire rhythmic bursts of action potentials during escape swimming behavior. We studied the role of the A1s in swimming behavior and pattern generation in whole animal and isolated CNS preparations. 2. The escape swim is a cyclic sequence of dorsal and ventral flexions of the body. Durin...

Sorting out Genes that Regulate Epithelial and Neuronal Polarity

Sorting Neuronal Proteins: Lessons from Epithelial Cells At an anatomical level, the polarities of neurons and epithelial cells appear quite different. In a motor neuron, a meter or more often separates axon terminals from David S. Bredt Department of Physiology School of Medicine University of California at San Francisco 513 Parnassus Avenue the soma and dendrites, whereas in polarized epithel...

Transcription factors and effectors that regulate neuronal morphology.

Transcription factors establish the tremendous diversity of cell types in the nervous system by regulating the expression of genes that give a cell its morphological and functional properties. Although many studies have identified requirements for specific transcription factors during the different steps of neural circuit assembly, few have identified the downstream effectors by which they cont...

Functional organization of neuronal and humoral signals regulating feeding behavior.

Energy homeostasis--ensuring that energy availability matches energy requirements--is essential for survival. One way that energy balance is achieved is through coordinated action of neural and neuroendocrine feeding circuits, which promote energy intake when energy supply is limited. Feeding behavior engages multiple somatic and visceral tissues distributed throughout the body--contraction of ...